Klonopin is a drug used to treat panic disorder and certain species of seizures. It has a long half-life and can remain in a person’s system for weeks.In studies, Klonopin to be detectable on a urine test for as much as a month, top top a hair test for approximately 28 days, and also on a saliva test for approximately 5 or 6 days.

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Abuse the Klonopin can lead to addiction and physical dependence. Human being who have come to be dependent on the drug need to work with a doctor or seeks treatment program to gradually reduce the sheep (taper), as stopping abruptly can be dangerous and even life-threatening.


How Is Klonopin Used?

Clonazepam, also known through the brand name Klonopin, is a prescription sedative medication supplied to treat scare disorder and seizure disorders. Specifically, that is aimed at dealing with Lennox-Gastaut syndrome, akinetic, and myoclonic seizures.1Klonopin is in the benzodiazepine class of drugs and also is thought to attain its results by improving the activity of the neurotransmitter gamma-aminobutyric mountain (GABA), i beg your pardon is the key inhibitory neurotransmitter in the brain.1

What are the Effects?

The intended result of Klonopin is to mitigate the occurrence of seizures or scare attacks. In spite of its therapeutic benefits, usage of the medicine may have actually some next effects, including:2Feelings that tirednessDepression (mostly discovered in adults).Irritability.Dizziness.Coordination and balance issues.Problems through concentration.Memory and attention problems.Nausea.Loss of appetite.Serious side results include:3Increased love rate.Low blood pressure.Respiratory depression.Difficulty breathing.Drowsiness.Impaired speaking.Loss of consciousness.Loss of satisfied (anhedonia).Depressed mood.Suicidal ideation.According to the national Alliance top top Mental condition (NAMI), many drugs may communicate with Klonopin.

Concurrent use of ketoconazole, itraconazole, nefazodone, fluvoxamine, and cimetidine may boost the blood levels and effects that clonazepam.3Concurrent usage of carbamazepine, phenytoin, and also phenobarbital may decrease levels of the drug, making Klonopin much less effective.3


Combining Klonopin and other benzodiazepines, alcohol, and also opioids deserve to lead to slowed breathing, coma, and death.


Likewise, combine Klonopin through alcohol, resting pills, opioids, anti-anxiety medications, antipsychotic medications, various other anticonvulsants, antidepressants, and also antihistamines can cause increased drowsiness. Combine Klonopin and other benzodiazepines, alcohol, and also opioids can likewise lead come slowed breathing, coma, and also death.3In addition to enduring adverse next effects, the is possible to overdose from acquisition too much clonazepam—and this risk is enhanced when it is linked with alcohol and other drugs. If you observe someone suffering an overdose, contact for emergency medical assist right away.

Signs and also symptoms of overdose include:1Poor reflexes.Confusion.Extreme drowsiness.Coma.Flumazenil is a drug that deserve to partially or completely reverse the effects of a clonazepam overdose. However, the is offered in emergency settings as a component of overdose treatment and not together a substitute because that it. By prevent the benzodiazepine impact of clonazepam, flumazenil management could an outcome in seizures in at risk patients—so it will be administered through the emergency team v caution.1

How long Does It remain in your Body?

Due to its lengthy half-life that 20-50 hours, clonazepam continues to be in the body for a much longer time than other drugs with fairly shorter half-lives. The half-life the a drug refers to the amount of time that takes a person’s human body to eliminate fifty percent of the dose.4
The complying with are some basic timeframes for how long Klonopin will show up ~ above different varieties of tests based on case studies.

It is vital to keep in mind that Klonopin may not present up on typical urine tests. The check may be able to show the the medicine is present, but it might not have the ability to determine the amount.5In one study, traces that clonazepam’s major metabolite 7-aminoclonazepam were detectable top top a urine test for approximately 3 weeks ~ a solitary 3mg dose, and also one that the attendees in the research tested optimistic 28 job after the critical dose. However, the mayo Clinic says that long-acting benzodiazepines such as clonazepam might be recognize in the urine for as much as 30 days.6,7In one study, 7-aminoclonazepam was detectable in the hair the 6 out of 10 participants after they take it a solitary 3mg dose. In 2 participants, it was detectable because that 28 days. In 2 participants, it to be detectable top top the 21st day, and in 2 participants, it was detectable ~ above the 28th day.8Saliva tests have a detection home window of approximately 5 and 6 days complying with last use.9
Individual factors can affect the result of a test, including:5,7Age.Gender.Health.Weight.pH that urine.Urine concentration.When the last dose was taken.Amount taken.Frequency the use.

How do You decoding From Klonopin?

Klonopin is a Schedule IV controlled substance, which method it has some potential for abuse and also physical or emotional dependence. Physical dependency can construct after simply 2 mainly of acquisition the medicine daily, defines the national Alliance ~ above Mental illness (NAMI). The is feasible to build some lot of physiological dependence even when taking the drug precisely as command by your doctor.3
If you have actually been abusing Klonopin, a clinical detox regimen can help ensure a safe withdrawal.


NAMI alerts that clonazepam use need to not be quit abruptly or without talk to your medical professional first. If quit too abruptly, unpleasant side results are likely to occur, and also some can even be life-threatening. Withdrawal symptom include:3,10Anxiety.Insomnia.Irritability.Dizziness.Sweating.Nausea.Vomiting.Changes in blood pressure.Increased love rate.Hallucinations.Tremors.Seizures.Withdrawal symptoms may not construct for more than a week, reach optimal intensity during the 2nd week, and fade throughout the third or 4th week.10If you have been taking the medicine under the care of a physician, you can work v them ~ above a tapering schedule to slowly reduce the dose. The encourage tapering schedule is to decrease the dose by 0.125mg every 3 days until you space no much longer taking the drug. However, talk to your medical professional to identify the ideal dose for you.1If you have actually been abusing Klonopin, a clinical detox routine can help ensure a safe withdrawal. These programs can help you for sure taper turn off the drug—as fine as any kind of other drugs you have been using—and treat any kind of complications the arise.

How easy Is that to come to be Addicted come Klonopin?

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Though the may have actually somewhat much less abuse potential than drugs such together opioids, cocaine, or methamphetamine, world can build an seeks to Klonopin and also other benzodiazepines if they frequently abuse them. Many world abuse them in mix with other drugs. For example, they may use them to intensify an opioid high, ease withdrawal native heroin or other opioids, increase the results of alcohol, and also self-manage alcohol withdrawal.11

People who come to be addicted to Klonopin and develop significant physical dependence could require the safety and supervision the a clinical detoxification program complied with by formal addiction treatment. There are countless options easily accessible for seeks treatment, consisting of inpatient and also outpatient programs. Programs often incorporate individual and group therapy, skill-building sessions, seeks education, clinical services, and continuing care plans.

Effective treatment programs recognize that no solitary treatment will work for everyone, and also treatment plans have to be personal tailored and continually reviewed and also updated. Treatment should also address any co-occurring substance use or mental health disorders in stimulate to avoid relapse.12 because that example, civilization who started taking Klonopin for scare disorder and began abusing it need treatment because that their scare disorder and also substance abuse. Otherwise, lock may start abusing substances again if their panic symptoms resurface.

If you’re prepared to get aid for an seeks to Klonopin or one more substance, start exploring your choices today.

Sources

<1>. Food and also Drug Administration. (2017). Klonopin tablets (clonazepam).

<2>. Epilepsy Foundation. Clonazepam.

<3>. National Alliance on psychological Illness. (2019). Clonazepam (Klonopin).

<4>. Epocrates. Clonazepam.

<5>. College of Rochester medical Center. Benzodiazepines (Urine).

<6>. Negrusz, A. Et al. (2003). Remove of 7-aminoclonazepam in urine ~ a single dose of clonazepam. Analytical and also Bioanalytical Chemistry, 376(8).

<7>. Moeller, K., Kissack, J., Atayee, R., and also Lee, K. (2017). Clinical translate of Urine medicine Tests: What Clinicians need to Know around Urine medicine Screens. Mayo Clinic Proceedings.

<8>. Negrusz, A. Et al. (2002). Deposition of 7-Aminoclonazepam and also Clonazepam in Hair adhering to a single Dose of Klonopin. Journal of analytical Toxicology, 26, 471-478.

<9>. Nordal, K., Oiestad, E.L., Enger, A., Christophersen, A.S., and also Vindenes, V. (2015). Detection times of Diazepam, Clonazepam, and also Alprazolam in oral Fluid collected From patients Admitted to Detoxification, after ~ High and Repeated drug Intake. Therapeutic drug Monitoring, 37(4), 451-460.

<10>. American Psychiatric Association. (2013). Diagnostic and also statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.

<11>. Longo, L., and Johnson, B. (2000). Addiction: component I. Benzodiazepines—Side Effects, Abuse Risk and also Alternatives. American household Physician, 61(7), 2121-2128.

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<12>. Nationwide Institute on medicine Abuse. (2019). Treatment approaches for medicine Addiction.