Beating a urine drug test isn’t basic task. And also that’s why most civilization tend come be hesitant at an initial about the idea of adding eye drops come urine come fool a test.

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That sounds means too simple and practically impractical, right?

But adding a few drops the Visine in a pee sample can indeed assist fool the test by leading to a false negative for THC, opiates, and also some other drugs.

However, this method is, hands down, risky, and also we’d never ever advocate for it.

In this article, I’ll it is in explaining how to usage eye drops to pass a drug test and also the scientific rationale of how and why the works.

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How Visine helps You to Beat a drug Test

Before delving depth into exactly how Visine changes drug check results, it’s important to note that almost any other eye autumn brand will certainly do.

It’s just that Visine is the most commonly used.

You can get that at any kind of drug store near you or indigenous Amazon for much less than ten bucks.

There space two methods through which eye drops job-related to assist you win a test;

Diluting the drug metabolitesHiding the THC metabolites to create a false negative

Diluting the drug Metabolites

Using Visine to cheat a urine test requires that you add a few drops directly into the urine sample (it should never be ingested).

As you carry out this, you’ll simply be adding more liquid right into the sample, in order to bringing the concentration the the drug metabolites down.

If excellent successfully, this can lower the concentration to listed below the cut-off level, thereby skewing the results to your favor.

Will this work?

Whether utilizing Visine eye drops as a dilution technique will work-related or not depends on the kind of test that you’ll it is in subjected to.

Whoever mandates girlfriend to take it a urinary drug test could either use basic Home drug Test strips for the test or send her specimen come the lab.

You’ll be in lucky if they’ll be using residence Drug Tests. These tests show whether you are hopeful or negative for the drugs the you room tested for.

They don’t suggest the metabolites" concentration level, and neither execute they test for other necessary urine contents such together the creatinine level and specific gravity that might be affected by dilution.

This means that you could easily pass the check if you have diluted the urine enough.

The other benefit here is that home Drug test don’t use complex tools.

Therefore, the risk of false positives is highly lessened too.

If the medicine testing firm is sending out your sample to the lab, utilizing Visine as a dilution an approach might no work.

This is due to the fact that the couple of drops added to the sample will interfere through the concentration of the drug metabolites, yet they will also alter the specimen"s temperature.

Even the simple EMIT tests will certainly detect the little variations in the temperature range of the urine in the laboratory.

If the rap technicians are encouraged that you’ve purposely diluted the specimen, the results may come out together FAILED as result of adulteration, or they may be forced to perform a GCMS check if they are paid to carry out so.

Hiding the medicine metabolites to produce a false negative

Other 보다 dilution, Visine and also other eye drop brands hide the drug metabolites in urine, thereby making castle less easily accessible for detection in tests.

The means Visine works here is a tiny bit complicated and fascinating in ~ the same time.

It is stated that Benzalkonium chloride, the main energetic ingredient in Visine, along with the aqueous systems of the eye drop, create hydrophobic and hydrophilic layers wherein they trap the medicine metabolites.

This provides them virtually invisible throughout detection, thereby resulting in a false negative.

Visine Will aid create a False Negative: clinical Evidence.

A most studies have been lugged out to prove that Visine does help create a false an unfavorable during urine drug tests.

One that the most generally referred functions of literature is Dr. Amitava Dasgupta’s work: A health and wellness Educator’s guide to understanding Drugs that Abuse Testing.

This guide lists Visine as the only over-the-counter drug that deserve to be effectively used to invalidate immunoassays when testing for drugs such as marijuana, cocaine, and also opiates, amongst other drugs.

Referring come a previous research that had been brought out to analyze the effects of Visine eye drop on drug screening and how system involved, Dr. Amitava notes that in low concentrations, Visine causes a false-negative since of its vital active ingredient: benzalkonium chloride.

This study argues that when several drops of Visine are included into a pee sample, a section of the marijuana metabolites (THC-COOH) is surprise in the eye drop"s aqueous solvent component. Simultaneously, the various other is ‘trapped in the hydrophobic internal of the benzalkonium chloride micelles.

Consequently, there room very few metabolites left because that detection in antibody-based assays.

However, it’s necessary to note that the usage of Visine come falsify urine test results only works with EMIT and also FPIA (Fluorescence Polarization Immunoassay) tests.

But the won’t it is in of any help in a GC/MS test. This study states that in a GC/MS test, the eye drop ingredient won’t have any effect or change in the THC metabolites available in a to pee specimen.

This way that you’ll fail the test, specifically if you’ve had actually an encounter with marijuana in the critical 2-3 weeks.

Fortunately, many labs rely on EMIT test credit transaction for that simplicity regarding the devices needed.

They only refer come GC/MS as a confirmatory test after you’ve tested optimistic with an EMIT test.

These findings are evidenced by yet another 1989 research study experiment whose findings were released on the national Institutes the Health.

This examine aimed come analyze just how Visine eye drops lead to a false-negative in to pee cannabinoid immunoassay screens.

In this experiment, the researchers included the adhering to drugs come drug-free to pee specimens to a concentration level double the cut-off level of each: 9-carboxy-THC, morphine, oxazepam, secobarbital, amphetamine, benzoylecgonine, and also phencyclidine.

Visine to be later added into the specimens prior to being screened for the drugs making use of EMIT and GC/MS tests.

The results proved that Visine led to a diminish in the concentration levels of all the drugs.

However, false-negative outcomes were derived for 9-carboxy-THC only. Also, only EMIT display tests provided false-negative results for cannabinoids.

This study also affirms the Visine go not influence the detection that the 9-carboxy-THC in the to pee specimen utilizing the GCMS tests.

These researchers went ahead and also wanted to identify whether the benzalkonium chloride micelles of Visine to be responsible because that the ‘absence’ that the cannabinoids in this tests.

To perform this, they described ultrafiltration researches where a pee sample with 9-carboxy-THC was applied to a centrifugal filtration system.

In the lack of Visine, that was discovered out the 60% the the 9-carboxy-THC passed v the membrane.

However, when Visine was added to the sample, just 10% the the drug can get with the membrane.

What go this mean?

The molar massive of a molecule of 9-carboxy-THC is 344.44 g/mol. Together such, and as expected, free and unassociated 9-carboxy-THC passes freely through a filter membrane with a molecule mass cut-off of 1000 Da.

The fact that the drug"s solubility reduce by 6 folds as soon as Visine is included only proves the the drug has an association through the Benzalkonium chloride micelles that Visine.

How much Visine is compelled to reason false-negative outcomes in a urine medicine test?

When trying to beat a urine drug test with any type of adulterant, understanding the specific amount that adulterant that you must use is paramount.

The Visine method is not exempted.

Most world think it’s essential to add as much Visine eye drops into the cup to guarantee a pass.

This is whereby they gain it wrong.

The researchers in the study over actually found out that adding a lot of Visine right into the urine go the opposite.

It did no take the concentration levels of the drug to below the cut-off.

Check the end the table below.

Visine con.


9-carboxy-THC con.



As the results over indicate, 100 milliliters that Visine every liter of to pee was required to reduced the 9-carboxy-THC to 35ug/L, i beg your pardon is an incredibly safer level for you.

However, copy the concentration the Visine had minimal effect on the concentration the the 9-carboxy-THC in the to pee specimen.

The researchers concluded that precisely 100 milliliters the Visine would certainly be compelled to create a false negative in a test whereby the specimen has actually 100ug/L.

So, considering that most labs expropriate the utmost 60ml the urine during a test, you would need to include in 6ml of Visine come thwart the results.

Anything above this beginning dwindling her odds of beating the test, as the table over proves.

Does adding eye drops come a urine sample aid pass a drug test today?

Adding eye drops into a urine specimen might aid in skirting the results to her favor. There room 2 significant strengths in this method.

First, when added to a urine sample, Visine just interferes v the pee temperature variety but go not change the concentration level of other important urine components; ph, particular gravity, and also creatinine.

Therefore, if girlfriend can control to ensure the the Visine is at par through your body temperature before including it in, it might guarantee a certain pass.

The second plus with this method is that Visine materials are not detectable by program urine verity analysis.

This to reduce the odds of being flagged even further.

Why us don’t recommend it

Albeit promising, we would certainly not introduce you to count on eye autumn if you have to pass that urine test.

This an approach has a couple of grey areas that do it a risky and challenging venture. Very first off, remember that the study above was brought out close to 3 decades ago.

Although Visine fooled the EMIT assays, these tests have been improved over time, and it might not work.

Secondly, the eye drops technique only works with EMIT immunoassays.

This means that if a false positive and also your specimen room forwarded for a GC/MS display screen for confirmation, the possibilities of beating it room close to zero.

Thirdly, together the research findings over show, come beat a THC drug test using Visine, you’ll need to be exact on the ratio of Visine included concerning the concentration that THC metabolites in the urine.

Moreover, through the increased attempts come fool urine tests with eye drops, many employers have now clarified the anyone who reflects up for a test v Visine in their pockets will certainly be based on an observed test.


Passing a urine drug test using Visine could have been viable a couple of decades ago, however it can not reduced it today.

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