In our latest question and also answer, the pharmacist discusses any type of potential medicine interactions between Benadryl (diphenhydramine) and prednisone.

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Marie asked

Can ns take Benadryl if I"m top top predisone?


There room no medicine interactions between Benadryl(diphenhydramine) and also prednisone. In fact, this two medicines are regularly usedtogether for details indications consisting of allergic reactions. In addition, there room no medicine interactions in between Benadryl and methylprednisolone or prednisolone, two various other steroids that are very comparable to prednisone and also used because that the very same indications.

Below is additional information around prednisone and also Benadryl.

Information AboutBenadryl

Benadrylis a first-generation antihistamine. Antihistamines space widely used forself-care the allergy symptoms including runny nose, watery eyes, sneezing, anditching the the nose, throat, or eyes. Benadryl may additionally be used for symptom ofthe usual cold, allergic reactions, occasional insomnia, and more.

Because Benadryl is a first-generation antihistamine, that ismore most likely to reason sedation and drowsiness. Various other first-generationantihistamines incorporate Dramamine (dimenhydrinate), Chlor-Trimeton(chlorpheniramine), Tavist (clemastine), and also Phenergan (promethazine), amongothers. These drugs cross theblood-brain barrier and have CNS effects like drowsiness and dizziness. Firstgeneration antihistamines can also cause urinary retention, GI upset, andblurry vision. The an initial generation antihistamines are also listed asmedications to protect against in elderly adult by the Beers Criteriadue come the boosted risk the confusion, dried mouth, and also drowsiness.

Second generation antihistamines encompass Claritin(loratadine), Cetirizine (Zyrtec), and also Allegra (fexofenadine) and also are lot lesssedating. This antihistamines are normally only supplied for treatment of allergysymptoms, conversely, Benadryl deserve to be supplied for a range of factors includingallergies, insect bites, toxicity ivy, sleep, and also motion sickness.

Information AboutPrednisone

Prednisoneis the most commonly prescribed oral corticosteroid. Prednisone was firstapproved by the FDA in 1955. Corticosteroids occupational by suppressing inflammationand the immune response. Prednisone and also other corticosteroids have a variety ofindications including asthma, COPD, general inflammatory conditions, and manymore.

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Short term usage of corticosteroids are usually welltolerated. Long term usage may cause a wide range of side results including impairedwound healing, muscle weakness, bone fractures, and hyperglycemia. After longterm use, abrupt discontinuation the corticosteroids should be avoided. Taperingthe dose may be crucial after lengthened therapy.

To conclude, diphenhydramine and also prednisone might be takentogether as there space no medicine interactions between the two commonly usedmedications.